Results of two separate studies taking place at Children’s Mercy Hospitals and Clinics can benefit physicians all over the world by helping them make use of genetic testing to prevent complications and ease the worry of new parents through predicting in advance as to which all of the newborns could be requiring hospital readmission shortly after birth.

The study results can also help physicians to identify which all of their young patients are expected to respond better or negligible to therapies involving steroids when it comes to treating asthma.

From Sciencedaily.com:

Up to 85 percent of hospital readmissions during the first two weeks of life are due to hyperbilirubinemia, more commonly recognized as jaundice. The condition can be concerning for new parents, and potentially devastating for the infant if not recognized and promptly treated. New research being led by Susan Abdel-Rahman, PharmD, professor of pediatrics at Children’s Mercy Hospitals and Clinics is identifying specific genetic markers that will enhance the ability to predict which newborns are at risk.

“This condition can be very harmful for newborn infants and scary for new parents,” said Dr. Abdel-Rahman. “Knowing in advance which babies are likely to experience symptoms can provide reassurance for parents and guidance for clinicians in determining which babies may benefit from more careful monitoring.”

The goal of the research is to develop an electronic tool that can be used by clinicians in nurseries nationwide to dramatically improve prediction of risk for hyperbilirubinemia and prevent complications due to late detection. The study will be among the largest of its kind, aiming to enroll 3,500 newborns.

The asthma research was led by Bridgette L. Jones, MD, allergy, asthma and immunology and clinical pharmacology specialist, and Carrie A. Vyhlidal, PhD, research scientist, pediatric clinical pharmacology, at Children’s Mercy Hospitals and Clinics, and a separate study was conducted by researchers at Children’s Mercy.

Tags:  asthma, jaundice, Steroids

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