Anabolic steroids can help dialysis patients
Wednesday 07, Apr 2010
The use of anabolic steroids by patients suffering kidney diseases may prove to be effective to increase lean muscle mass besides minimizing the fatigue level to a significant extent, as per a new study.
Kidney disease patients tend to experience malnutrition and an accompanying loss of muscle mass and these side effects have been associated in the past with an increased mortality.
From Bio-Medicine.Org:
A team of University of California San Francisco researchers, led by Kirsten L. Johansen, M.D., UCSF assistant professor of medicine, epidemiology & biostatistics, studied a group of patients who were receiving dialysis and were suffering from malnutrition.
In a randomized, double blind trial, 29 patients were given either the anabolic steroid nandrolone decanote or a placebo (dummy medication) for a six-month period. All of the patients were receiving dialysis treatments at San Francisco General Hospital. At the end of the trial, patients receiving the anabolic steroid gained an average of 5.7 pounds more lean body mass than the patients who got the placebo. Also, the patients who received the steroid reported less fatigue and scored better on physical performance tests. The researchers’ results are published in the April 14 issue of the Journal of the American Medical Association (JAMA).
Hemodialysis, the most common form of dialysis in the United States, is a medical procedure employed when a patient’s kidneys cannot properly clean the blood of toxins and waste products. A patient’s blood is removed from the body via a tube inserted in a vein, filtered by a dialysis machine, and then replaced. Typically, this process must be repeated three times a week and takes three to four hours. In some cases, dialysis is considered a “bridge” while the patient is awaiting a kidney transplant - which can be up to a three year wait in the US.
This study was supported by grants from the National Center for Research Resources, the National Institute of Diabetes and Digestive and Kidney Diseases, and the Bay Area Nutrition Center.
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The increasing rate of mortality among patients with kidney disease became the main concern of a recent study. Patients with kidney problems often experience malnutrition and loss of muscle mass due to the disease and its treatment called dialysis.